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. 2020 Jul 13;43(9):2176–2182. doi: 10.2337/dc20-0611

Table 1.

Mixed effect model analysis on EGP and glucose disappearance

EGP (μmol/kg FFM/min) Rd (μmol/kg FFM/min)
EuLoI EuHiI HyLoI EuLoI EuHiI HyLoI
Exercise for participants without versus participants with type 1 diabetes
  Estimated differences −14.3 3.2 −18.2 36.2 36.7 79.8
  95% CI (−21.0, −7.5) (−3.0, −9.5) (−24.5, −12.0) (10.3, 62.1) (12.9, 60.4) (56.1, 103.6)
  P value 0.0001 0.30 <0.0001 0.0067 0.0030 <0.0001
Pre-exercise versus exercise
 Participants without diabetes
  Estimated differences −9.6 −6.2 −3.9 −57.0 −55.4 −91.2
  95% CI (−14.6, −4.6) (−11.2, −1.2) (−8.9, 1.1) (−77.0, −37.1) (−75.3, −35.4) (−111.1, −71.2)
  P value 0.0002 0.0149 0.123 <0.0001 <0.0001 <0.0001
 Participants with type 1 diabetes
  Estimated differences −19.2 −2.5 −9.0 −40.2 −70.4 −42.3
  95% CI (−25.3, −13.1) (−7.5, 2.5) (−14.0, −4.0) (−64.6, −15.7) (−30.5, −5.0) (−62.2, −22.3)
  P value <0.0001 0.33 0.0005 0.0015 <0.0001 0.0001
EuLoI versus EuHiI EuLoI versus HyLoI EUHiI versus HyLoI EuLoI versus EuHiI EuHiI versus HyLoI EhHyI versus HyLoI
Exercise
 Participants without diabetes
  Estimated differences 3.8 9.7 5.9 −37.4 −65.1 −27.8
  95% CI (−1.2, 8.8) (4.7, 14.7) (0.9, 10.9) (−57.3, −17.4) (−45.2, −6.5) (−47.7, −7.8)
  P value 0.137 0.0002 0.0204 0.0003 <0.0001 0.0068
  Participants with type 1 diabetes
 Estimated differences 21.3 5.8 −15.6 −36.9 −21.5 15.4
  95% CI (15.7, 26.9) (0.1, 11.4) (−20.5, −10.6) (−59.4, −14.4) (−44.0, 1.0) (−4.6, 35.3)
  P value <0.0001 0.0452 <0.0001 0.0015 0.061 0.130