Figure 6. Architecture of the human OSTM1 luminal domain.

(A) Monomeric structure of the hsOSTM1 luminal domain. Disulfide bonds are shown as pink sticks and glycosylated asparagine residues are shown as sticks. (B) Domain topology of hsOSTM1 with disulfides depicted as pink lines. (C) hsOSTM1 dimer interface. Residues that mediate inter-protomer interactions are colored in wheat. (D) Inter-protomer interaction between D150 of protomer A and R107 of protomer B. Protomer A is colored yellow and protomer B is colored grey.