Table 4.
Univariable cox-regression analyses for the composite endpoint
| Univariable analysis |
|||
|---|---|---|---|
| HR | 95% CI | P-value | |
| Age at CMR (years) | 1.01 | 0.95–1.07 | 0.74 |
| NT-proBNP (μmol/L) | 1.03 | 1.00–1.05 | 0.030 |
| QRS duration (ms) | 1.01 | 0.99–1.04 | 0.41 |
| Rest CMR | |||
| LVEDV (mL/m2) | 1.02 | 0.97–1.08 | 0.43 |
| LVESV (mL/m2) | 0.86 | 0.93–1.09 | 0.86 |
| LVEF (%) | 1.01 | 0.92–1.11 | 0.82 |
| RVEDV (mL/m2) | 0.99 | 0.97–1.01 | 0.22 |
| RVESV (mL/m2) | 0.98 | 0.95–1.01 | 0.094 |
| RVEF (%) | 1.04 | 0.95–1.04 | 0.83 |
| RV mass volume ratio (g/mL) (↑0.1) | 1.40 | 0.32–6.02 | 0.65 |
| Relative change during stress | |||
| LVESV (%) | 1.04 | 0.99–1.09 | 0.086 |
| LVEF (%) | 0.98 | 0.92–1.04 | 0.42 |
| RVEDV (%) | 1.07 | 1.01–1.15 | 0.036 |
| RVESV (%) | 1.06 | 1.01–1.12 | 0.016 |
| RVEF (%) | 0.94 | 0.89–0.99 | 0.043 |
| Abnormal stress response | 10.5 | 2.48–44.78 | 0.001 |
CMR, cardiac magnetic resonance imaging; EDV, end-diastolic volume; EF, ejection fraction; ESV, end-systolic volume; LV, left ventricle; RV, right ventricle; SV, stroke volume.