Table 1.
Main characteristics of patients on admission to the ICU.
| Characteristics | Patients (n = 43) |
|---|---|
| Median age, years (IQR) | 64 [56–70] |
| Sex, male, no. (%) | 37 (86) |
| Median BMI, kg/m2 (IQR) | 27 [26–30] |
| Comorbidities, no. (%) | |
| Hypertension | 31 (72) |
| Heart failure | 1 (2.3) |
| ARBS | 17 (39.5) |
| Coronary disease | 5 (11.6) |
| Diabetes mellitus | 16 (37.0) |
| Pulmonary disease | 7 (16.0) |
| Immunosuppression | 3 (7.0) |
| Severity of illness | |
| Duration from onset of symptoms to ICU admission, days (IQR) | 8.5 [5.3–11.6] |
| SAPS II (IQR) | 37 [28–49] |
| SOFA score on day 1 (IQR) | 5 [4–7] |
| Acute kidney injury, no. (%) | 28 (65.1) |
| KDIGO 1 | 6 (13.9) |
| KDIGO 2 | 6 (13.9) |
| KDIGO 3 | 16 (34.9) |
| Renal replacement therapy, no. (%) | 8 (18.6) |
| Mechanical ventilation on ICU admission, no. (%) | 37 (86) |
| ARDS, no. (%) | 43 (100) |
| Ratio of PaO2 to FiO2, mm Hg (PaO2/FiO2) at admission (IQR) | 136 [82.5–174.5] |
| Ratio of PaO2 to FiO2 nadir, mm Hg (IQR) | 82 [70–103] |
| Median number of prone position ventilation sessions (IQR) | 1 [0–2] |
| Duration of mechanical ventilation, days (IQR) | 10 [7–12] |
| Use of noradrenaline during the first 48 h, no. (%) | 36 (83.7) |
| Length of stay in ICU, days (IQR) | 11 [8–13] |
| Death, no. (%) | 12 (27.9) |
| Admission biological data | |
| WBC count, ×109 cells/L (IQR) | 9.52 [5.2–12.4] |
| Lymphocyte count, ×109 cells/L (IQR) | 0.79 [0.5–1.1] |
| Serum creatinine concentration, μmol/L (IQR) | 75 [57–100.5] |
| D-dimers, ng/mL (IQR) | 2610 [1490–4820] |
| Radiological data | |
| X-ray, number of dials affected at admission | 4 [2–4] |
| CT during hospitalization, no. (%) | 29 (67.4) |
| 10–25a | 2 (6.9) |
| 25–50a | 9 (31.0) |
| 50–75a | 10 (34.5) |
| >75a | 8 (27.6) |
| Antimicrobial treatment, no. (%) | |
| Antibiotic therapy before admission | 29 (67.4) |
| Third-generation cephalosporin | 22 (51.1) |
| Macrolide | 21 (48.3) |
| Other antibiotics | 11 (25.6) |
BMI = body mass index; ICU = intensive care unit; SAPS II = Simplified Acute Physiology Score II; SOFA = Sepsis-Related Organ Failure Assessment; KDIGO = Kidney Disease Improving Global Outcomes; ARDS = acute respiratory distress syndrome; ARBS = angiotensin–renin–aldosterone blocker system; WBC = white blood cells; CT = computerized tomography.
a
Specific COVID-19 pulmonary lesions.