Table 1.
Dynamics of the patients’ fever and respiratory condition during the administration of favipiravir.
| Case | Day after onset | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Oxygen administration | 14 L/min | MV 70% |
MV 70% |
V-V ECMO | V-V ECMO | V-V ECMO | V-V ECMO | V-V ECMO | V-V ECMO | V-V ECMO | MV 50% |
MV 50% |
MV 40% |
5 L/min |
| SpO2 (%) | 88 | 97 | 91 | 98 | 98 | 95 | 95 | 97 | 99 | 95 | 94 | 96 | 96 | 93 | |
| Body temperature (°C) | 37.6 | 38.5 | 39.0 | 36.5 | 36.1 | 36.7 | 36.5 | 36.1 | 36.8 | 36.9 | 37.0 | 37.5 | 36.6 | 37.1 | |
| 2 | Oxygen administration | 6 L/min | 8 L/min | 5 L/min | 6 L/min | 5 L/min | 5 L/min | 4 L/min | 2 L/min | 3 L/min | 1 L/min | 1 L/min | 1 L/min | 1 L/min | 1 L/min |
| SpO2 (%) | 97 | 96 | 96 | 99 | 95 | 98 | 95 | 91 | 95 | 95 | 95 | 94 | 95 | 94 | |
| Body temperature (°C) | 37.6 | 37.7 | 38.1 | 37.3 | 38.0 | 37.0 | 36.8 | 36.6 | 36.8 | 36.3 | 36.2 | 36.4 | 36.7 | 36.5 | |
| 3 | Oxygen administration | 6 L/min | NHF 80% |
NHF 100% |
NHF 80% |
NHF 70% |
NHF 70% |
NHF 70% |
NHF 70% |
NHF 60% |
NHF 60% |
NHF 60% |
NHF 40% |
NHF 40% |
4 L/min |
| SpO2 (%) | 97 | 94 | 95 | 94 | 96 | 97 | 95 | 96 | 94 | 97 | 95 | 98 | 99 | 99 | |
| Body temperature (°C) | 37.2 | 38.3 | 38.2 | 36.6 | 36.0 | 36.6 | 36.8 | 36.5 | 37.3 | 36.0 | 37.1 | 36.0 | 37.1 | 37.0 |
MV: mechanical ventilation; SpO2: oxygen saturation; V-V ECMO: veno-venous extracorporeal membrane oxygenation; NHF: nasal high flow.