Table 2.
Frequency of mismatches between 15,001 SARS-CoV-2 genome sequences and 15 sets of oligonucleotides from early lab developed tests. The Charite group - RdRP, Japan NIID - N, and China CDC - N assays were further analyzed due to extensive mismatches..
| Assay | 0 mismatches |
1 mismatches |
2 mismatches |
3+ mismatches |
|---|---|---|---|---|
| Charité group - N | 98.9 % | 0.9 % | 0.0 % | 0.1 % |
| Charité group - RdRP | 0.0 % | 99.6 % | 0.3 % | 0.0 % |
| Charité group - E | 99.6 % | 0.2 % | 0.1 % | 0.0 % |
| China CDC - N | 79.9 % | 1.0 % | 0.0 % | 19.0 % |
| China CDC - orf1ab | 99.1 % | 0.8 % | 0.0 % | 0.0 % |
| HKU - N | 98.9 % | 0.9 % | 0.1 % | 0.1 % |
| HKU - orf1b-nsp14 | 99.5 % | 0.4 % | 0.0 % | 0.0 % |
| Japan NIID - N | 0.0 % | 99.5 % | 0.5 % | 0.0 % |
| Pasteur - RdRP-IP2 | 99.5 % | 0.2 % | 0.3 % | 0.0 % |
| Pasteur - RdRP-IP4 | 99.5 % | 0.4 % | 0.1 % | 0.0 % |
| Thailand NIH - N | 99.1 % | 0.4 % | 0.2 % | 0.3 % |
| CDC USA - N1 | 97.6% | 0.6 % | 0.1 % | 1.7 % |
| CDC USA - N2 | 99.3% | 0.6 % | 0.0 % | 0.0 % |
| CDC USA - N3 | 98.4% | 1.4 % | 0.0 % | 0.1 % |
| BCCDC PHL - RdRP | 99.7 % | 0.3 % | 0.0 % | 0.0 % |