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. 2020 Aug 20;10:292. doi: 10.1038/s41398-020-00887-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Red colors show voxels in the amygdala where we found significant reductions in neural activity when comparing early to late trials (stimulus by time contrast). Green colors show voxels in the amygdala where we found significant association between amygdala reductions to fear relevant cues (spider: early>late contrast) and approach behavior during the incentive conflict task 24 h after repeated exposure. Results are displayed on the standard MNI template. b Using extracted average beta-values for the entire amygdala ROIs we found significant decreases for fear-relevant but not neutral cues in both the left and right amygdala. Points and error-bars show mean and SEM. c Scatterplots show the correlation between left and right amygdala decreases respectively and approach behavior at 24-h time point. The amygdala values reflect decreases (spiders: early>late contrast) in the peak voxel from the voxel-wise regression analysis. The association was significant and similar in the left and right amygdala (left: r = 0.48; p < 0.001; right: r = 0.45; p = 0.002).