Table 1.

Overexpression of DEK in squamous cell carcinoma (SCC)

Histology	Method	Cases	% cases	Authors (References)
Cervical scc	IHC	≧ 1 (98)	≧ 1 (96.1%)	Wu et al. [39]*
		≧ 2 (82)	≧ 2 (80.4%)
Lung SCC	IHC		47.90%	Wang et al. [41]**
HNSCC	IHC		100%	Adams et al. [46]***
OSCC	IHC		88%	Nakashima et al. [19]****

*Immunostaining was zero (negative), or < 5% positive cells; one (weak positive), 5–25% positive cells; two (intermediate positive), 26–50% positive cells; three (strong positive), > 50% positive cells. Only nuclear expression was considered as positive staining

**Intensity of DEK nuclear staining was also scored as zero (no staining), one (weak), or two (marked). Percentage scores were assigned as one (1–25%), two (26–50%), three (51–75%), and four (76–100%). The scores were multiplied to give a final score of 0–8, and the total expression of DEK was determined as either negative or low expression (− ; score < 4) or overexpression (+ ; score ≥ 4)

***Number of cells with positive staining was quantified as: three (≥ 90% positive tumor cells), two (10–50% positive tumor cells), or one (< 10% positive tumor cells). The intensity of DEK staining was determined as W (weak), V (variable), or S (strong)

****Number of cells with positive staining scored as: one (0–25%), two (26–50%), three (51–75%), and four (76–100%). The expression of DEK was determined as either negative or low expression (1–2) or overexpression (3–4)