Table 2.
Baseline patient and tumor characteristics stratified by MVR category, in which combined MVRs were assigned to the different categories based on hierarchy of surgical complications
| Gastrointestinala (n = 55) |
Urologicb (n = 14) |
Solid organc (n = 14) |
Abd. wall/omentum/ovariesd (n = 47) |
p value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | % | n | % | n | % | n | % | |||
| Gender | Male | 35 | 63.6 | 8 | 57.1 | 8 | 57.1 | 18 | 38.3 | 0.080 |
| Female | 20 | 36.4 | 6 | 42.9 | 6 | 42.9 | 29 | 61.7 | ||
| Age | ≤ 70 | 33 | 60.0 | 8 | 57.1 | 9 | 64.3 | 17 | 36.2 | 0.070 |
| > 70 | 22 | 40.0 | 6 | 42.9 | 5 | 35.7 | 30 | 63.8 | ||
| ASA | I–II | 35 | 70.0 | 11 | 84.6 | 5 | 50.0 | 29 | 72.5 | 0.361 |
| III–IV | 15 | 30.0 | 2 | 15.4 | 5 | 50.0 | 11 | 27.5 | ||
| Hospital | UZ Leuven | 16 | 29.1 | 2 | 14.3 | 2 | 14.3 | 14 | 29.8 | 0.125 |
| St. Antonius | 11 | 20.0 | 5 | 35.7 | 3 | 21.4 | 20 | 42.6 | ||
| Radboud UMC | 17 | 30.9 | 6 | 42.9 | 5 | 35.7 | 8 | 17.0 | ||
| Amsterdam UMC | 11 | 20.0 | 1 | 7.1 | 4 | 28.6 | 5 | 10.6 | ||
| Tumor related complications* | No | 50 | 92.6 | 12 | 100.0 | 12 | 92.3 | 40 | 93.0 | > 0.99 |
| Yes | 4 | 7.4 | 0 | 0.0 | 1 | 7.7 | 7 | 7.0 | ||
| Emergency setting | No | 46 | 83.6 | 14 | 100.0 | 12 | 85.7 | 40 | 85.1 | 0.517 |
| Yes | 9 | 16.4 | 0 | 0.0 | 2 | 14.3 | 7 | 14.9 | ||
| Tumor location | Right/transverse | 26 | 47.3 | 1 | 7.1 | 4 | 28.6 | 31 | 66.0 | < 0.001 |
| Left | 29 | 52.7 | 13 | 92.9 | 10 | 71.4 | 16 | 34.0 | ||
| Surgical procedure | (Extended) right hemicolectomy | 23 | 41.8 | 1 | 7.1 | 4 | 28.6 | 30 | 66.7 | < 0.001 |
| (Extended) left hemicolectomy | 7 | 12.7 | 1 | 7.1 | 6 | 42.9 | 3 | 6.7 | ||
| (Low) anterior/sigmoid resection/subtotal colectomy | 25 | 45.5 | 12 | 85.8 | 4 | 28.5 | 12 | 25.6 | ||
| Approach | Open | 43 | 78.2 | 13 | 92.9 | 13 | 92.9 | 36 | 76.6 | 0.405 |
| Laparoscopic | 12 | 21.8 | 1 | 7.1 | 1 | 7.1 | 11 | 23.4 | ||
| N-stage | N0 | 41 | 74.5 | 6 | 46.2 | 8 | 57.1 | 24 | 51.1 | 0.027 |
| N1 | 11 | 20.0 | 3 | 23.1 | 5 | 35.7 | 11 | 23.4 | ||
| N2 | 3 | 5.5 | 4 | 30.8 | 1 | 7.1 | 12 | 25.5 | ||
| Radicality | R0 | 49 | 90.7 | 13 | 92.9 | 11 | 84.6 | 40 | 88.9 | 0.857 |
| R1 | 5 | 9.3 | 1 | 7.1 | 2 | 15.4 | 5 | 11.1 | ||
| Grade | Well differentiated | 40 | 75.5 | 10 | 76.9 | 11 | 78.6 | 32 | 68.1 | 0.835 |
| Poorly differentiated | 10 | 18.9 | 3 | 23.1 | 3 | 21.4 | 14 | 29.8 | ||
| Mucinous/signet ring cell | 3 | 5.7 | 0 | 0.0 | 0 | 0.0 | 1 | 2.1 | ||
| Adjuvant chemotherapy | Yes | 23 | 42.6 | 7 | 50.0 | 6 | 46.2 | 13 | 27.7 | 0.290 |
| No | 31 | 57.4 | 7 | 50.0 | 7 | 53.8 | 34 | 72.3 | ||
aGastrointestinal = any gastrointestinal MVR, including combinations with other MVR categories
bUrologic = urologic MVR not combined with gastrointestinal MVR, but including other categories
cSolid organ= MVR including (part) of a solid organ, not combined with gastrointestinal or urologic MVR, but including abd. wall/omentum/ovaries MVR
dAbd. wall/omentum/ovaries = abdominal wall/omentum/ovaries MVR only, not combined with other categories
*Tumor-related complications included preoperative complication of ileus, anemia, and abscesses