TABLE 2.
Multivariate Cox Proportional Hazard Analysis Examining Factors Associated With Treatment Failure in Biologic-Treated Patients With Ulcerative Colitis
| Variables | Hazard Ratio | 95% CI | P |
|---|---|---|---|
| Prior TNFα antagonist exposure (yes vs no) | 0.75 | 0.46–1.23 | 0.25 |
| Disease duration (per 1 y) | 0.95 | 0.91–0.99 | 0.016 |
| Body mass index (per 1-kg/m2 increase) | 1.04 | 1.00–1.08 | 0.047 |
| Concomitant immunomodulators (yes vs no) | 0.65 | 0.41–1.02 | 0.063 |
| Albumin (per 1 g/dL) | 0.66 | 0.45–0.99 | 0.045 |
| Prior prednisone use (yes vs no) | 1.85 | 0.93–3.67 | 0.078 |