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. 2020 Aug 20;11(8):665. doi: 10.1038/s41419-020-02893-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Correlation of CASC4 and PCSK7 mRNA expression levels (in z-scores) in the METABRIC patients’ data set. b Association of the expression levels of CASC4 and PCSK7 genes with the survival patients’ rate. c qPCR analysis of hCASC4, hPCSK7, and hFurin in MCF10a and MDA-MB-231 cells. d Western blot analysis and quantifications of cell lysates from MCF10a or MDA-MB-231 cells. P-values: **P < 0.01, n.s. not significant (two-sided Student’s t-test). All experiments were repeated at last three times and center values represent the mean ± standard error from the mean.