Table 1.
Baseline ocular surface parameters of Rheumatoid Arthritis (RA) patients compared to healthy controls.
| RA patients (n = 16) | Control (n = 24) | p | |
|---|---|---|---|
| OSDI (score) | 22.9 (11.4–41.7) | 1.0 (0–8.3) | 0.007 |
| OSDI abnomal, n (%) | 11 (68.8) | 4 (16.7) | 0.002 |
| Schirmer (mm/5 min) | 14.5 (10–20) | 27 (17–33) | 0.005 |
| Schirmer < 10 mm, n (%) | 6 (37.5) | 2 (8.3) | 0.042 |
| TBUT (seconds) | 9 (6–12) | 8 (6.5–10) | 0.70 |
| TBUT < 10 s, n (%) | 11 (68.8) | 15 (62.5) | 0.68 |
| Fluorescein (score) | 0 (0–0) | 0 (0–0) | 0.99 |
| Lissamine green (score) | 0 (0–0) | 0 (0–0) | 0.65 |
| MGD, n (%) | 8 (50) | 2 (8.3) | 0.007 |
| IC (score) | 1 (0.5–2) | 0 (0–0) | < 0.001 |
| IC abnomal, n (%) | 12 (75) | 2 (8.3) | 0.001 |
| GCC (cells/mm2) | 325 (274–707) | 742 (562–863) | 0.004 |
| Dry eye, n (%) | 13 (81.3) | 1 (4.2) | < 0.001 |
| Severity, n | |||
| Absent | 3 (18.7) | 23 (95.8) | |
| Mild | 12 (75) | 1 (4.2) | < 0.001 |
| Moderate | 1 (6.3) | 0 | |
Data are expressed as medians (interquartile range) or absolute numbers (percentage). RA rheumatoid arthritis, OSDI Ocular Surface Disease Index (range 0–100), mm millimeters; Schirmer’s test range 0–35 mm, TBUT tear break-up time; Fluorescein and Lissamine green scores range 0–9, MGD meibomian gland dysfunction, IC impression cytology (range 0–3), GCC goblet cell count; Bold values: statistical significance = p < 0.05.