1.
1 939例研究对象的临床特征
Clinical characteristics of 1 939 study subjects
| Items | Control (n=1 093) | Isolate COPD (n=62) | Isolate OSA (n=735) | Overlap syndrome (n=49) | P value |
| Data is represented by median (interquartile range) or n (%). AHI, apnea-hypopnea index; COPD, chronic obstructive pulmonary disease; OSA, obstructive sleep apnea. | |||||
| Age/years | 56 (45, 66) | 69 (59, 77) | 64 (54, 73) | 69 (63, 76) | <0.001 |
| Male | 531 (48.6) | 38 (61.3) | 507 (69.0) | 31 (63.3) | <0.001 |
| Lowest saturation/% | 87 (83, 89) | 84 (81, 86) | 81 (76, 85) | 78 (71, 84) | <0.001 |
| AHI/(event/h) | 5 (2, 8) | 6 (2, 9) | 32 (21, 53) | 52 (25, 85) | <0.001 |
| Body mass index/(kg/m2) | 25.9 (22.3, 30.6) | 28.0 (23.5, 33.2) | 28.2 (24.4, 32.3) | 29.0 (26.2, 34.6) | <0.001 |
| Diabetes | 166 (15.2) | 22 (35.5) | 142 (19.3) | 25 (51.0) | <0.001 |
| Hypertension | 394 (36.1) | 37 (59.7) | 377 (51.3) | 35 (71.4) | <0.001 |
| Coronary artery disease | 176 (16.1) | 32 (51.6) | 174 (23.7) | 22 (44.9) | <0.001 |
| History of smoking | 711 (65.1) | 51 (82.3) | 462 (62.9) | 36 (73.5) | 0.011 |
| Cerebrovascular disease | 26 (2.4) | 1 (1.6) | 40 (5.4) | 2 (4.1) | 0.005 |
| Renal disease | 23 (2.1) | 2 (3.2) | 19 (2.6) | 0 | 0.602 |
| Heart failure | 46 (4.2) | 8 (12.9) | 62 (8.4) | 13 (26.5) | <0.001 |