2.
Male mice genotype | Female mice | Plugged mice | Pregnant mice | Offspring (M ∶F) | AOA | FCP/% | FC/% |
M, male; F, female; WT, wild type. Average offspring amount (AOA) was calculated as the total number of offspring divided by the number of females that gave birth to offspring. Frequency of copulatory plug (FCP) was calculated as the ratio of the number of plugged females to total number of females to which males with the same genotype had access. Frequency of conception (FC) was calculated as the ratio of the number of females that gave birth to offspring to total number of females.*P<0.001. | |||||||
CMTM2+/+ (n=5) CMTM2+/- (n=5) CMTM2-/-(n=5) |
WT (n=49) WT (n=51) WT (n=50) |
38 34 36 |
31 13 0* |
249 (132 ∶117) 103 (50 ∶53) 0* |
8.0 7.9 0* |
77.6 66.7 72.0 |
63.3 25.5 0* |