Table 3.

Association between pulse wave velocity and accelerated global cognitive decline during follow-up

Pulse wave velocity	No. participants	The 20%a of participants with the greatest cognitive decline over the follow-up, N (%)	Odds ratiob (95% CI) P value
Lowest third	1316	224 (17.2%)	1.0 (Ref)
Middle third	1300	265 (20.4%)	1.23 (1.01, 1.51) 0.04
Highest third	1212	281 (23.2%)	1.40 (1.13, 1.73) 0.002
Effect per 1 SD increase	3828	770 (20.1%)	1.11 (1.02, 1.21) 0.02

^aThe cut-points for those with the greatest cognitive decline are age, sex and employment grade specific and are based upon the 3828 participants in this analysis

^bOdds ratios of being in the group with the greatest cognitive decline are adjusted for age, sex, ethnicity and employment grade