Table 1.
Annual incidence rates and prevalence of Wilson’s disease.
| Population | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | Total | |
|---|---|---|---|---|---|---|---|---|---|
| Incidence rates (per million person-years) | |||||||||
| New patients | 50,515,666 | 235 (4.7) | 186 (3.7) | 238 (4.7) | 182 (3.6) | 177 (3.5) | 153 (3) | 162 (3.2) | 1,333 (3.8) |
| Sex | |||||||||
| Men | 25,310,385 | 126 (5) | 102 (4) | 135 (5) | 110 (4.3) | 114 (4.5) | 91 (3.6) | 90 (3.6) | 768 (4.3) |
| Women | 25,205,281 | 109 (4.3) | 84 (3.3) | 103 (4.1) | 72 (2.9) | 63 (2.5) | 62 (2.5) | 72 (2.9) | 565 (3.2) |
| Age (years) | |||||||||
| 0–19 | 11,606,790 | 89 (7.7) | 75 (6.5) | 84 (7.2) | 80 (6.9) | 88 (7.6) | 76 (6.5) | 82 (7.1) | 574 (7.1) |
| 20–29 | 6,866,956 | 53 (7.7) | 40 (5.8) | 53 (7.7) | 40 (5.8) | 32 (4.7) | 27 (3.9) | 28 (4.1) | 273 (5.7) |
| 30–39 | 8,370,549 | 46 (5.5) | 27 (3.2) | 32 (3.8) | 24 (2.9) | 21 (2.5) | 20 (2.4) | 20 (2.4) | 190 (3.2) |
| 40–49 | 8,844,352 | 30 (3.4) | 22 (2.5) | 34 (3.8) | 15 (1.7) | 16 (1.8) | 6 (0.7) | 12 (1.4) | 135 (2.2) |
| 50–59 | 7,066,823 | 11 (1.6) | 12 (1.7) | 26 (3.7) | 13 (1.8) | 13 (1.8) | 17 (2.4) | 15 (2.1) | 107 (2.2) |
| 60–69 | 4,191,329 | 3 (0.7) | 5 (1.2) | 6 (1.4) | 6 (1.4) | 6 (1.4) | 6 (1.4) | 3 (0.7) | 35 (1.2) |
| 70–79 | 2,618,525 | 3 (1.1) | 3 (1.1) | 3 (1.1) | 3 (1.1) | 1 (0.4) | 1 (0.4) | 2 (0.8) | 16 (0.9) |
| ≥ 80 | 950,342 | 0 (0) | 2 (2.1) | 0 (0) | 1 (1.1) | 0 (0) | 0 (0) | 0 (0) | 3 (0.5) |
| Prevalence rates (per million people) | |||||||||
| Total patients | 50,515,666 | 1,415 (28) | 1589 (31.5) | 1817 (36) | 1984 (39.3) | 2,149 (42.5) | 2,285 (45.2) | 2,430 (48.1) | 13,669 (38.7) |
| Sex | |||||||||
| Men | 25,310,385 | 814 (32.2) | 909 (35.9) | 1,040 (41.1) | 1,140 (45) | 1,247 (49.3) | 1,329 (52.5) | 1,405 (55.5) | 7,884 (44.5) |
| Women | 25,205,281 | 601 (23.8) | 680 (27) | 777 (30.8) | 844 (33.5) | 902 (35.8) | 956 (37.9) | 1,025 (40.7) | 5,785 (32.8) |
| Age (years) | |||||||||
| 0–19 | 11,606,790 | 513 (44.2) | 587 (50.6) | 669 (57.6) | 745 (64.2) | 831 (71.6) | 907 (78.1) | 989 (85.2) | 5,241 (64.5) |
| 20–29 | 6,866,956 | 405 (59) | 442 (64.4) | 495 (72.1) | 534 (77.8) | 565 (82.3) | 591 (86.1) | 615 (89.6) | 3,647 (75.9) |
| 30–39 | 8,370,549 | 300 (35.8) | 324 (38.7) | 353 (42.2) | 373 (44.6) | 393 (47) | 407 (48.6) | 422 (50.4) | 2,572 (43.9) |
| 40–49 | 8,844,352 | 126 (14.2) | 148 (16.7) | 179 (20.2) | 192 (21.7) | 205 (23.2) | 209 (23.6) | 219 (24.8) | 1,278 (20.6) |
| 50–59 | 7,066,823 | 47 (6.7) | 56 (7.9) | 82 (11.6) | 93 (13.2) | 105 (14.9) | 118 (16.7) | 131 (18.5) | 632 (12.8) |
| 60–69 | 4,191,329 | 14 (3.3) | 18 (4.3) | 23 (5.5) | 27 (6.4) | 31 (7.4) | 34 (8.1) | 36 (8.6) | 183 (6.2) |
| 70–79 | 2,618,525 | 8 (3.1) | 11 (4.2) | 13 (5) | 16 (6.1) | 16 (6.1) | 17 (6.5) | 16 (6.1) | 97 (5.3) |
| ≥ 80 | 950,342 | 2 (2.1) | 3 (3.2) | 3 (3.2) | 4 (4.2) | 3 (3.2) | 2 (2.1) | 2 (2.1) | 19 (2.9) |
†2010 year standard population.