Table 3.
Mortality rates (%) during follow-up among patients with Wilson’s disease.
| Year (Patients) | 2010 (N = 1,415) | 2011 (N = 1589) | 2012 (N = 1817) | 2013 (N = 1984) | 2014 (N = 2,149) | 2015 (N = 2,285) | 2016 (N = 2,430) | Total (N = 13,669) |
|---|---|---|---|---|---|---|---|---|
| Annual mortality, number (rate, %) | ||||||||
| No of fatal cases | 12 (0.9) | 10 (0.6) | 15 (0.8) | 12 (0.6) | 17 (0.8) | 17 (0.7) | 19 (0.8) | 102 (0.7) |
| Sex | ||||||||
| Men | 7 (0.9) | 4 (0.4) | 10 (1.0) | 7 (0.6) | 9 (0.7) | 14 (1.1) | 7 (0.5) | 58 (0.7) |
| Women | 5 (0.8) | 6 (0.9) | 5 (0.6) | 5 (0.6) | 8 (0.9) | 3 (0.3) | 12 (1.2) | 44 (0.7) |
| Age (years) | ||||||||
| 0–19 | 1 (0.2) | 2 (0.3) | 4 (0.6) | 2 (0.3) | 0 (0) | 0 (0.) | 0 (0) | 9 (0.2) |
| 20–29 | 3 (0.7) | 0 (0) | 1 (0.2) | 1 (0.2) | 1 (0.2) | 4 (0.7) | 5 (0.8) | 15 (0.4) |
| 30–39 | 3 (1.0) | 3 (0.9) | 4 (1.1) | 1 (0.3) | 6 (1.5) | 5 (1.2) | 3 (0.7) | 25 (0.9) |
| 40–49 | 0 (0) | 3 (2.0) | 2 (1.1) | 3 (1.6) | 2 (1.0) | 2 (1.0) | 4 (1.8) | 16 (1.2) |
| 50–59 | 3 (6.4) | 0 (0) | 2 (2.4) | 1 (1.1) | 4 (3.8) | 2 (1.7) | 5 (3.8) | 17 (2.5) |
| 60–69 | 1 (7.1) | 1 (5.6) | 2 (8.7) | 2 (7.4) | 3 (9.7) | 1 (2.9) | 2 (5.6) | 12 (6.2) |
| 70–79 | 0 (0) | 1 (9.1) | 0 (0) | 1 (6.3) | 0 (0) | 3 (17.7) | 0 (0) | 5 (4.9) |
| ≥ 80 | 1 (50.0) | 0 (0) | 0 (0) | 1 (25.0) | 1 (33.3) | 0 (0) | 0 (0) | 3 (14.3) |
†The mortality rate was calculated by dividing the number of death cases in the corresponding year by the patients with Wilson’s disease from 2010 to 2016.