Table 4.
Clinical characteristic of patients diagnosed with Wilson’s disease between 2010 and 2016.
| Valuables | No of patients (%) Total = 1,333 |
No of death (%) Total = 52 |
Univariate analysis | P value | |
|---|---|---|---|---|---|
| HR | 95%CI | ||||
| Age, years (mean SD) | 26.1 ± 17.2 | 44.5 ± 19.3 | 1.00 | 0.00–0.00 | < 0.0001 |
| Men sex | 768 (57.7) | 31 (4.0) | 1.09 | 0.63–1.91 | 0.753 |
| Liver failure | 38 (2.9) | 9 (17.3) | 6.55 | 3.18–13.46 | < 0.0001 |
| Liver cirrhosis | 163 (12.2) | 24 (46.2) | 5.47 | 3.15–9.51 | < 0.0001 |
| Medical treatment | 465 (34.9) | 21 (40.4) | 1.14 | 0.65–3.01 | 0.640 |
| Penicillamine | 124 (9.3) | 14 (11.3) | 1.00 | ||
| Penicillamine + zinc | 21 (1.6) | 0 (0.0) | 0.00 | 0.00 | 0.997 |
| Penicillamine + zinc + trientine | 53 (4.0) | 2 (3.8) | 0.34 | 0.08–1.50 | 0.157 |
| Penicillamine + trientine | 45 (3.4) | 4 (8.9) | 0.84 | 0.28–2.58 | 0.764 |
| Zinc | 48 (3.6) | 0 (0.0) | 0.00 | 0.00 | 0.995 |
| Zinc + trientine | 98 (7.4) | 0 (0.0) | 0.00 | 0.00 | 0.993 |
| Trientine | 76 (5.7) | 1 (1.3) | 0.12 | 0.02–0.95 | 0.044 |
| Liver transplantation | 56 (4.2) | 3 (5.4) | 1.28 | 0.40–4.12 | 0.674 |
| BCT | 854 (64.1) | 30 (57.7) | 1.28 | 0.49–1.49 | 0.574 |
SD, standard deviation; BCT, best conservative treatment.