Skip to main content
. 2020 Aug 11;61(10):20. doi: 10.1167/iovs.61.10.20

Figure 4.

Figure 4.

CxCl10 inhibits endothelial cell proliferation in vitro and in vivo. (A) MTT assay results of HUVECs after exposure to CxCl10 (537.5 ng/mL) under basal (EBM) and growth (EGM) stimulating conditions. n = 3 independent experiments, two-way ANOVA, *P < 0.05. (B) Endothelial cell sprouting of HUVECs in response to CxCl10 (537.5 ng/mL) under diverse proangiogenic stimuli (n = 14–28 spheroids per group, two-way ANOVA, *P < 0.05). (D) NV at P18 following intravitreal injection of CxCl10 (500 ng) in Vldlr–/– at P12. n = 19 mice, two-sided Student's t-test: *P < 0.05. (E) CNV area 7 days postlaser following intravitreal injection of CxCl10 (500 ng) 1 day after laser treatment. n = 13 eyes, two-sided Student's t-test: *P < 0.05.