Effects of upregulating and downregulating TRIM59 expression on cell proliferation. (A, B) The growth curve and inhibition percentage of HXO-Rb44 cells from CCK8 assay, indicating that HXO-Rb44 cell growth was suppressed after silencing TRIM59. *P < 0.05, **P < 0.01 compared with the siNC group. (C, D) The growth curve and inhibition percentage of Y79 cells, suggesting that overexpression of TRIM59 promoted the cellular proliferation of Y79 cells. *P < 0.05, **P < 0.01 compared with vector-transfected Y79 cells.