Table 3. Receiver operator characteristic curve analysis of hub gene expression for PCRC.

Gene symbol	PCRC
	AUC	P-value	95%CI	ODT
CLCA4	0.987max	<0.001***	0.962–0.981	124.500
GUCA2A	0.985	<0.001***	0.952–0.963	138.500
GCG	0.963	<0.001***	0.833–0.962	23.100
SST	0.978	<0.001***	0.852–0.989	51.200
MS4A12	0.968	<0.001***	0.903–0.963	121.500
PLP1	0.968	<0.001***	0.889–0.973	64.050
CHGA	0.947	<0.001***	0.844–0.907	49.900
PYY	0.895	<0.001***	0.796–0.876	20.450
VIP	0.910	<0.001***	0.860–0.907	73.700
GUCA2B	0.919	<0.001***	0.833–0.925	92.800

AUC: area under curve; ^max the maximum of AUC; *Significant variables; ODT: Optimal diagnostic threshold;

PCRC: primary colorectal cancer.***: P<0.001.