Table 5.

Changes in clinical winners (highest value of n4) per model and disease target x considering observer O1 and O2.

Disease target x	Model	Differences in clinical winner max (n4) according to observers	Treatment z1 search query	Treatment z2 search query	n1	n2	n3	n4
epilepsy	Skip-gram	Observer O2a: New	valproate	levetiracetam	2	10	9	7
arthritis	CBOWb	Observer O2: n4 different	plus_methotrexate	methotrexate	1	12	9	6
arthritis	CBOW	Observer O2: New	methotrexate	DMARDsc	2	11	9	6
arthritis	Skip-gram	Observer O2: New	IACId	DMARDs	2	9	6	5
arthritis	Skip-gram	Observer O2: New	plus_methotrexate	DMARDs	2	10	6	5
anaemia	Skip-gram	Observer O1e: n4 different	recombinant_human_erythropoietin	iron	2	11	8	4

^aO2: BMJ health informatician who works with BMJ Best Practice content and has a junior doctor background.

^bCBOW: Continuous Bag-of-Words.

^cDMARD: disease-modifying antirheumatic drug.

^dIACI: intra-articular corticosteroid injection.

^eO1: medical consultant.