Table 3.
Multiple-factor binary logistic regression analysis of an influence of chosen independent variables including plasma level of OPG, pFN, proMMP-2, and proMMP-9 as predictors of the risk of endarterectomy.
| Independent variables | B | S.E. | Wald | P | Odds ratio |
|---|---|---|---|---|---|
| OPG | 3.47248 | 1.30591 | 7.0706 | 0.0078# | 32.2166 |
| Hypertension | 3.67218 | 1.15123 | 10.1747 | 0.0014# | 39.3375 |
| Sex (male) | 0.20183 | 1.00707 | 0.04017 | 0.8412 | 1.2236 |
| Smoking (current) | 1.75103 | 1.17237 | 2.2308 | 0.1353 | 5.7605 |
|
| |||||
| pFN | -0.0063167 | 0.0036775 | 2.9504 | 0.0859 | 0.9937 |
| Hypertension | 3.55459 | 1.21174 | 8.6051 | 0.0034# | 34.9736 |
| Sex (male) | 1.05097 | 1.10861 | 0.8987 | 0.3431 | 2.8604 |
| Smoking (current) | 2.83889 | 1.31857 | 4.6355 | 0.0313# | 17.0968 |
|
| |||||
| proMMP-2 | 5.66930 | 3.41510 | 2.7558 | 0.0969 | 289.8325 |
| Hypertension | 2.65427 | 1.24455 | 4.5485 | 0.0329# | 14.2147 |
| Sex (male) | 0.15236 | 1.20924 | 0.01587 | 0.8997 | 1.1646 |
| Smoking (current) | 3.02960 | 1.76443 | 2.9482 | 0.0860 | 20.6890 |
| WBC | 1.18472 | 0.39212 | 9.1284 | 0.0025# | 3.2698 |
|
| |||||
| proMMP-9 | 0.41722 | 2.60737 | 0.02561 | 0.8729 | 1.5177 |
| Hypertension | 3.16472 | 1.15277 | 7.5368 | 0.0060# | 23.6821 |
| Sex (male) | 0.79772 | 1.15184 | 0.4796 | 0.4886 | 2.2205 |
| Smoking (current) | 2.40338 | 1.54465 | 2.4210 | 0.1197 | 11.0605 |
| WBC | 0.93230 | 0.33800 | 7.6080 | 0.0058# | 2.5403 |
# P < 0.05 was considered statistically significant. B: regression coefficient; S.E.: standard error; OPG: osteoprotegerin; pFN: plasma fibronectin; proMMP-2: matrix metalloproteinase 2 proenzyme; proMMP-9: matrix metalloproteinase 9 proenzyme; and WBC: white blood cells.