Table 3. Search results of clinical trial registration.

	Registration number	Title	Phase	Conditions	Interventions	Locations
1	NCT02615457	Huaier Granule in Treating Women With Triple Negative Breast Cancer	IV	Triple Negative Breast Cancer	Huaier Granule	Qilu hospital of Shandong University, Ji'nan, Shandong, China
2	NCT02627248	Neoadjuvant Chemotherapy With or Without Huaier Granule in Treating Women With Locally Advanced Breast Cancer That Can Be Removed By Surgery	IV	Breast Cancer	Huaier Granule Other: Chemotherapy	Qilu hospital of Shandong University, Ji'nan, Shandong, China
3	ChiCTR1800015390	Huaier Granule for Stage II and III Triple Negative Breast Cancer with lymph node metastasis: A Multicenter Randomized, Double-blind, Placebo-controlled Clinical Trial	IV	Triple Negative Breast Cancer	Huaier Granule	The First Afliliated Hospital of AMU (Southwest hospital), Chongqing, China
4	ChiCTR-OIC-16007737	A multicenter, double -blind, randomized, placebo-controlled study on stage II-III triple-negative breast cancer with lymph node metastasis treated by Huaier granules	I	Breast cancer	Huaier Granule	Southwest Hospital, The third Military Medical University, Chongqing, China
5	ChiCTR-TRC-11001250	Extract of Fungi of Huaier used for triple negtive breast cancer—a prospective randomized controlled trial	IV	Triple Negative Breast Cancer	Huaier Granule	Southwest Hospital, The third Military Medical University, Chongqing, China