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. 2020 Aug 20;20:402. doi: 10.1186/s12935-020-01491-6

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Lasso Cox and Kaplan–Meier analysis. a Lines of different colors represent different genes. With the increase of lambda value, the coef of some genes become zero, indicating that they do not affect the model. b The deviance of the cross validation. When the partial likelihood deviance is minimum, the corresponding model is the best. c The co-expression heat map of 11 genes. Red indicates a positive correlation, blue indicates a negative correlation, and the cross indicates no statistical significance. d The heatmap of Kaplan–Meier analysis results of 11 genes. Red means high expression of the gene lead to worse prognosis, blue means low expression of the gene lead to worse prognosis, grey means there are no significance of the analysis, p < 0.05 means it is statistically significant. The darker of the color shows the smaller of the p-value. e Kaplan–Meier analysis of ELOVL4 in TCGA-BLCA. f Kaplan–Meier analysis of FABP6 in TCGA-BLCA