Table 1.

Parameters used in simulations

Parameter name	Symbol	Default	Range	Unit	Source
Arteriolar radius	R1	12	5 to 20	µm	[49– 51]
PVS length	La	250	250 to 500	µm	[50, 145]
PVS width	wd	3	2–10	µm	[16, 42, 43]
CSF viscosity	µf	0.001	–	Pa.s	[47, 48]
CSF density	ρf	1000	-	kg/m3	[47, 48]
PVS porosity	ζ	0.8	0.5–0.9	–	[16, 17, 146]
PVS permeability	ks	2 × 10−14	7 × 10−13 to 2 × 10−15	m2	[12, 14, 45, 46]
Brain section radius	R3	150	100–200	µm	[145, 147]
Brain shear modulus	µs	4	1–8	kPa	[29–32, 63–66]
Brain tissue density	ρ1	1000	–	kg/m3	[148]
Pulsation amplitude (% arteriolar radius)	b1	1	0.5–2	–	[16]
Pulsation frequency	f	10	7–14	Hz	[72]
Pulse wave speed	c	1	0.5–10	m/s	[69–71]
Pulse wave wavelength	λ	0.1	0.03–1.43	m	c/f
Diffusion coefficient	D	1.4 × 10−6	–	cm2/s	[134, 135]