Table 2.
A hierarchical regression of serum UA predicting cognitive function in patients with CHF (n = 192)
| Cognitive function | ||||||
|---|---|---|---|---|---|---|
| β | 95% CI | R2 | ΔR2 | P-value | ||
| Lower | Upper | |||||
| Block 1 | – | – | – | 0.584 | – | 0.000** |
| Age | −0.353 | − 0.474 | − 0.231 | 0.000** | ||
| Gender | −0.101 | −0.213 | 0.012 | 0.080 | ||
| Educational level | 0.297 | 0.188 | 0.406 | 0.000** | ||
| NYHA function class | −0.035 | −0.145 | 0.076 | 0.536 | ||
| LVEF | 0.013 | −0.100 | 0.125 | 0.825 | ||
| BMI | 0.070 | −0.041 | 0.180 | 0.214 | ||
| Hemoglobin | −0.084 | −0.208 | 0.040 | 0.184 | ||
| hs-CRP | −0.188 | −0.292 | − 0.084 | 0.000** | ||
| eGFR | −0.002 | −0.111 | 0.107 | 0.967 | ||
| Hypertension | −0.073 | −0.177 | 0.032 | 0.171 | ||
| Type 2 diabetes mellitus | −0.009 | −0.108 | 0.090 | 0.852 | ||
| Atrial fibrillation | −0.080 | −0.190 | 0.030 | 0.154 | ||
| SDS score | −0.261 | −0.379 | − 0.142 | 0.000** | ||
| Block 2 | – | – | – | 0.598 | 0.014 | 0.015* |
| Serum UA | −0.130 | −0.235 | − 0.025 | 0.015 | ||
UA uric acid, CHF chronic heart failure, NYHA New York Heart Association, LVEF left ventricular fraction, BMI body mass index, hs-CRP hypersensitive C-reactive protein, eGFR estimated glomerular filtration rate, SDS self-rating depression scale
β standardized coefficients, CI confidence interval
* P < 0.05; ** P < 0.01