Table 4.
A hierarchical regression of serum UA predicting cognitive function in female CHF patients (n = 71)
| Cognitive function | ||||||
|---|---|---|---|---|---|---|
| β | 95% CI | R2 | ΔR2 | P-value | ||
| Lower | Upper | |||||
| Block 1 | – | – | – | 0.672 | – | 0.000** |
| Age | −0.479 | −0.677 | − 0.282 | 0.000** | ||
| Educational level | 0.334 | 0.173 | 0.495 | 0.000** | ||
| NYHA function class | −0.026 | −0.209 | 0.157 | 0.774 | ||
| LVEF | 0.140 | −0.041 | 0.320 | 0.128 | ||
| BMI | 0.073 | −0.111 | 0.257 | 0.430 | ||
| Hemoglobin | 0.005 | −0.184 | 0.193 | 0.961 | ||
| hs-CRP | −0.234 | −0.415 | − 0.053 | 0.012* | ||
| eGFR | −0.128 | −0.317 | 0.062 | 0.183 | ||
| Hypertension | −0.115 | −0.291 | 0.061 | 0.195 | ||
| Type 2 diabetes mellitus | 0.008 | −0.164 | 0.180 | 0.925 | ||
| Atrial fibrillation | 0.033 | −0.142 | 0.208 | 0.704 | ||
| SDS score | −0.260 | −0.451 | − 0.070 | 0.008** | ||
| Block 2 | – | – | – | 0.672 | 0.000 | 0.955 |
| Serum UA | −0.005 | −0.185 | 0.175 | 0.955 | ||
UA uric acid, CHF chronic heart failure, NYHA New York Heart Association, LVEF left ventricular fraction, BMI body mass index, hs-CRP hypersensitive C-reactive protein, eGFR estimated glomerular filtration rate, SDS self-rating depression scale
β standardized coefficients, CI confidence interval
* P < 0.05; ** P < 0.01