Table 2.
Intraoperative Data
|
Crystalloids (n = 58) |
Colloids (n = 62) |
p - Value | |
|---|---|---|---|
| Duration of Anesthesia, min | 330 ± 121 | 307 ± 117 | 0.29 |
| Duration of Surgery, min | 281 ± 118 | 250 ± 113 | 0.14 |
| Fluid management | |||
| Total Fluid Intake, mLa | 4519 (3382–4824) | 3247 (2495–4210) | < 0.001° |
| Crystalloid, mL | 3905 (2880–5288) | 1557 (1207–2116) | < 0.001° |
| Colloid, mL | 0 (0–0) | 1250 (750–1938) | < 0.001° |
| Estimated Blood Loss, mL | 500 (100–1000) | 400 (100–875) | 0.23 |
| Transfusion yes/no (%) | 3/55 (5/95) | 6/56 (10/90) | 0.58 |
| Urinary Output, mL | 350 (300–500) | 405 [250, 615] | 0.82 |
| Anesthesia Management | |||
| Fentanyl, mcg | 1000 [800, 1200] | 850 (623–1223) | 0.39 |
| TWA Et Sevoflurane, % | 1.8 (1.6–1.9) | 1.8 (1.6–2.0) | 0.88 |
| Core Temperature, °C | 36.4 ± 0.4 | 36.4 ± 0.5 | 0.98 |
| ICU Admission yes/no (%) | 36/22 (62/38) | 36/26 (58/42) | 0.71 |
| Hemodynamic | |||
| TWA MAP, mmHg | 77 ± 6 | 75 ± 8 | 0.77 |
| TWA HR, beats.min−1 | 73 ± 12 | 70 ± 11 | 0.30 |
| TWA FTc, ms | 339 (321–353) | 348 (334–364) | 0.009° |
| TWA SV, mL | 76 (64–90) | 91 (75–106) | < 0.001° |
| TWA CO, L.min− 1 | 5.4 ± 1.2 | 6.2 ± 1.5 | 0.002° |
| Phenylephrine yes/no (%) | 54/4 (93/7) | 53/9 (85/15) | 0.24 |
Intraoperative data are presented as means ± SD, medians (IQR) or as counts for the categorical outcomes. Means were compared with an unpaired two-sided t-tests or Mann-Whitney-U tests as appropriate, medians with Wilcoxon rank-sum tests and counts with chi-square or Fisher’s exact tests. ° represents statistical significance (P < 0.05)
Abbreviations: Et end tidal, ICU intensive care unit, TWA time weighted average, MAP mean arterial pressure, HR heart rate, FTc corrected flow time, SV stroke volume, CO cardiac output, SD standard deviation
a Total fluid intake includes baseline, fluid boluses, antibiotics, analgesics and additional fluid, administered at the discretion of attending anesthesiologist