Table 2.

Labs and Tumor Properties on Imaging and Histopathology

Factor	Total (N = 136)
	n	n (%) or Median [P25, P75]
Random GH level at Dx	125	8.2[3.2,34.0]
IGF-1 level at Dx	134	769.0[567.0,956.0]
2-h nadir post OGTT GH at Dx	44	4.4[1.6,16.9]
Most recent random GH level	128	0.61[0.31,1.8]
Most recent IGF-1 level	134	205.5[155.0,281.0]
Most recent 2-h nadir post OGTT GH	32	0.32[0.19,0.90]
Months between GH measures	116	21.5[7.9,65.3]
Months between IGF-1 measures	131	34.7[12.8,87.9]
Tumor size	135
• Macroadenoma		111(82.2)
• Microadenoma		24(17.8)
Tumor length/antero-posterior	126	16.0[11.0,22.0]
Tumor width/transverse	116	16.0[10.5,20.0]
Tumor height/craniocaudal	105	14.0[10.0,20.0]
GH staining	136	124(91.2)
GH staining type	65
• Rare		29(44.6)
• Diffuse		36(55.4)
Pituitary hormone co-staining	136	89(65.4)
• TSH	136	57(41.9)
• Prolactin	136	57(41.9)
• ACTH	136	12(8.8)
• FSH	136	4(2.9)
Granulation pattern	23
• Densely		17(73.9)
• Sparsely		6(26.1)
Cavernous sinus invasion	132	59(44.7)
Optic chiasm compression	132	43(32.6)