Table 3.
Adjusted relative risk for live-birth according to cleavage-stage embryo quality stratified by EMT, and EMT stratified by cleavage-stage embryo quality
| EMT | Q1 (n=770) | Q2 (n=2620) | Q3 (n=3315) | Q4 (n=3154) | Q5 (n=2993) | Q6 (n=1384) |
|---|---|---|---|---|---|---|
| <11 mm | ||||||
| N live-births/N cycles (LBR per cycle, %) | 68/574 (11.8) | 457/1775 (25.7) | 759/2104 (36.1) | 754/1702 (44.3) | 803/1642 (48.9) | 318/796 (39.9) |
| aRR (95%CI) a | 1.00 (reference) | 1.86 (1.43–2.41) | 2.38 (1.84–3.09) | 2.85 (2.17–3.75) | 3.13 (2.38–4.12) | 3.67 (2.74–4.91) |
| ≥11 mm | ||||||
| N live-births/N cycles (LBR per cycle, %) | 36/196 (18.4) | 345/845 (40.8) | 589/1211 (48.6) | 836/1452 (57.6) | 826/1351 (61.1) | 295/588 (50.2) |
| aRR (95%CI) a | 1.00 (reference) | 2.05 (1.43–2.94) | 2.35 (1.64–3.37) | 2.68 (1.86–3.86) | 2.78 (1.93–4.00) | 2.75 (1.89–4.01) |
| aRR (95%CI) b | 0.95 (0.61–1.46) | 1.23 (1.09–1.40) | 1.18 (1.07–1.29) | 1.22 (1.13–1.32) | 1.17 (1.08–1.26) | 1.12 (0.98–1.27) |
Abbreviations: N Number, LBR Live-birth rate, aRR Adjusted relative risk, CI Confidence interval
a Adjusted for maternal age, maternal BMI, basal FSH, basal LH, basal T, basal PRL, duration of infertility, infertility type, male factor of infertility, anovulation factor of infertility, Gn dosage, Gn duration, cycle protocols, E2 on hCG day, year of transfer, oocytes retrieved, location of fertility centers and number of embryos transferred. Reference was Q1 group
b Adjusted for maternal age, maternal BMI, basal FSH, basal LH, basal T, basal PRL, duration of infertility, infertility type, male factor of infertility, anovulation factor of infertility, Gn dosage, Gn duration, cycle protocols, E2 on hCG day, year of transfer, oocytes retrieved, location of fertility centers and number of embryos transferred. Reference was EMT <11 mm group