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. 2020 Aug 20;21:563. doi: 10.1186/s12891-020-03552-3

Table 1.

Characteristics of the included studies

Study Subjects
(n)
Age (years)
mean (SD)
Weight (kg) /height (cm)/BMI
(kg/m2)
mean (SD)
Activity level Sport Functional
task
Follow-up Outcomes Results Quality score
Smeets et al. 2019 [42]

ACL injury: 4 females

Controls: 35 females

ACL injury: 21 (3)

Controls:20.7 (3)

ACL injury: 62.6 (6.9)/172 (10)/ 21.2 (1.0)

Controls: 64.9 (7.5)/172 (9)/ 22.1 (1.6)

Elite Soccer, handball, volleyball Double-leg vertical drop jump 1 year

3D knee abduction angle (mean across entire landing phase)

Peak knee abduction moment

No difference in baseline 3D knee abduction angle or peak knee abduction moment between those who sustained an ACL injury and controls 11/19 (58%)
Räisänen et al. 2018 [37]

ACL injury: 4 females

Controls:265 (125 females)

15.7 (1.8) 64.6 (10)/173.3 (9.1)/NR U21 Floorball, basketball Single-leg squat 1 year 2D knee abduction angle NR* 15/19 (79%)
Numata et al. 2018 [40]

ACL injury: 27 females

Controls: 27 females

ACL injury: 15 (0)

Controls: 15 (0)

ACL injury: 57.4 (7.2)/161.2 (7.1)/ 22.1 (1.5)

Controls: 54.3 (5.4)/159.2 (5.8)/ 21.4 (1.9)

High school team sport

Basketball,

Handball

Single-leg vertical drop jump 3 years 2D medial displacement (IC, peak, excursion) Those who sustained an ACL injury had greater baseline MKD at IC and greater peak MKD compared to controls. MKD excursion NR 14/19 (73%)
Krosshaug et al. 2016 [20]

ACL injury: 30 females

Controls: 613 females

ACL injury: 19.9 (2.8)

Controls: 21.0 (3.9)

ACL injury: 64.6 (7.8)/168 (6.3)/NR

Controls: 66.3 (7.9)/169.5 (6.4)/NR

Elite Soccer, handball Double-leg vertical drop jump 1-7 years

3D knee abduction angle (IC)

2D medial displacement (excursion)

Peak knee abduction moment

No difference in baseline knee abduction at IC, peak knee abduction or MKD between those who sustained an ACL injury and controls 16/19 (84%)
Leppänen et al. 2017 [39]

ACL injury: 15 females

Controls*: 327 females

15.4 (1.9) 167.7 (6.2)/60.8 (8.0)/NR Junior league Basketball, floorball Double-leg vertical drop jump 3 years

3D knee abduction angle (IC)

2D medial displacement (excursion)

Peak knee abduction moment

No difference between baseline knee abduction at IC, peak knee abduction or knee abduction moment between those who sustained an ACL injury and controls 15/19 (79%)
Dingenen et.al 2015 [38]

ACL injury: 4 females

Controls: 40 females

ACL injury: 20.2 (2.9)

Controls: 20.8 (3.5)

ACL injury: 61.4 (7.3)/169.1 (10.2)/ 21.4 (1.3)

Controls: 64.2 (7.7)/170.7 (8.4)/ 22.1 (2.4)

Elite Soccer, handball, volley ball Single-leg vertical drop jump 1 year 2D knee abduction angle NR 14/19 (73%)
Goerger et al. 2015 [41]

ACL injury: 12 (4 females)

Controls: 39 (19 females)

ACL injury: 18.6 (0.5)

Controls: 18.5 (0.5)

ACL injury: 72.6 (9.5)/174.1 (7.3)/NR

Controls: 70.2 (13.)/172.6 (9.1)/ NR

Military NA Double-leg vertical drop jump 3 years 3D knee abduction angle (IC, peak) No difference between baseline knee abduction at IC, peak knee abduction or knee abduction moment between those who sustained an ACL injury and controls 14/19 (73%)
Nilstad et al. 2014 [35]

ACL injury: 4 females

Controls: 134 females

21.5 (4.1) 62 (6) /167 (5)/NR Elite Soccer Double-leg vertical drop jump 1 Year 3D knee abduction angle (peak) NR 15/19 (79%)
Hewett et al. 2005 [17]

ACL injury: 9 females

Controls*: 390 females

ACL injury: 15.8 (1.0)

Controls: 16.1 (1.7)

ACL injury: 61.5 (8.3)/167.7 (6.8)/ NR

Controls: 59.1 (8.1)/164.1 (6)/ NR

High school team sport Soccer, basket-ball, volley-ball Double-leg vertical drop jump 1 Year

3D knee abduction angle (IC, peak)

Peak knee abduction moment

Those who sustained an ACL injury had greater baseline knee abduction at IC, peak knee abduction and peak knee abduction moment compared to controls 12/19 (63%)

MKD = medial knee displacement in centimeters, IC = initial contact, * = number of knees, BMI = bodymass index, NR = not reported, * = some studies did not have risk factors for ACL injury as a specific aim and did, thus, not report the result for that variable. For these studies, the data were either retrieved from the authors of that specific study or, were possible, calculated by the authors of this review