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. Author manuscript; available in PMC: 2020 Aug 21.
Published in final edited form as: Trends Analyt Chem. 2019 Apr 30;116:300–307. doi: 10.1016/j.trac.2019.04.021

Figure 4.

Figure 4

(A) Linear dynamic range achieved by coupling reversed-phase LC separations with 18 m SLIM SUPER IM-MS separations and 2 s in-SLIM ion accumulation. Mobility filtering of phosphopeptides analytes of interest from background matrix ions at (B) 1nM concentration and (C) 50 pM concentration. (D) Much longer path length multilevel SLIM implementations are presently being developed to permit greatly increased peak capacity for broad and high peak capacity applications. Reprinted with permission from [32].