Table 7.

Predicted toxicity profile of EGCG, TF3, TF2b, TF2a, and remdesivir.

S. No.	Compounds name	Toxicity prediction
		Properties	Predicted values
1	EGCG	AMES toxicity	No
		Maximum tolerated dose (Human)	0.441 (log mg/kg/day)
		hERG I inhibitor	No
		hERG II inhibitor	Yes
		Oral rat acute toxicity (LD50)	2.522 (mol/kg)
		Oral rat chronic toxicity (LOAEL)	3.065 (log mg/kg_bw/day)
		Hepatotoxicity	No
		Skin sensitivity	No
		T. pyriformis toxicity	0.285 (µg/L)
		Minnow toxicity	7.713 log mM
2	TF3	AMES toxicity	No
		Maximum tolerated dose (Human)	0.438 (log mg/kg/day)
		hERG I inhibitor	No
		hERG II inhibitor	Yes
		Oral rat acute toxicity (LD50)	2.482 (mol/kg)
		Oral rat chronic toxicity (LOAEL)	7.443 (log mg/kg_bw/day)
		Hepatotoxicity	No
		Skin sensitivity	No
		T. pyriformis toxicity	0.285 (µg/L)
		Minnow toxicity	9.738 log mM
3	TF2b	AMES toxicity	No
		Maximum tolerated dose (Human)	0.438 (log mg/kg/day)
		hERG I inhibitor	No
		hERG II inhibitor	Yes
		Oral rat acute toxicity (LD50)	2.482 (mol/kg)
		Oral rat chronic toxicity (LOAEL)	5.322 (log mg/kg_bw/day)
		Hepatotoxicity	No
		Skin sensitivity	No
		T. pyriformis toxicity	0.285 (µg/L)
		Minnow toxicity	8.685 log mM
4	TF2a	AMES toxicity	No
		Maximum tolerated dose (Human)	0.439 (log mg/kg/day)
		hERG I inhibitor	No
		hERG II inhibitor	Yes
		Oral rat acute toxicity (LD50)	2.484 (mol/kg)
		Oral rat chronic toxicity (LOAEL)	5.035 (log mg/kg_bw/day)
		Hepatotoxicity	No
		Skin sensitivity	No
		T. pyriformis toxicity	0.285 (µg/L)
		Minnow toxicity	4.898 log mM
5	Remdesivir	AMES toxicity	No
		Maximum tolerated dose (Human)	0.15 (log mg/kg/day)
		hERG I inhibitor	No
		hERG II inhibitor	Yes
		Oral rat acute toxicity (LD50)	2.043 (mol/kg)
		Oral rat chronic toxicity (LOAEL)	1.639 (log mg/kg_bw/day)
		Hepatotoxicity	Yes
		Skin sensitivity	No
		T. pyriformis toxicity	0.285 (µg/L)
		Minnow toxicity	0.291 log mM