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Clinical characteristics of mutation subtypes.
| Genes | Biochemistry | Radiology | Molecular imaging |
|---|---|---|---|
| SDHx, FH | NE, MT, dopamine | MRI | 18F-FDG or 68Ga-Som PET |
| VHL, EPAS1 | NE | CT | 18F-DOPA or 11C-HED PET |
| RET | NE, E | CT | 18F-DOPA or 11C-HED PET |
NE, norepinephrine; E, epinephrine; FDG, fluorodeoxyglucose; Som, somatostatin receptor; DOPA, L-dihydroxyphenylalanine; HED, hydroxyephedrine; CT, computed tomography; MRI, magnetic resonance imaging; PET, positron emission tomographyMT, methoxytyramine.
