Table 3.
Linear B-cell epitopes and T-cell epitopes of S proteins with their antigenicity scores.
| No | B-cell Epitope | Position | B cell Epitope Vaxijen score | Promiscuous T-cell Epitopes | Number of bound alleles in MHC I + MHC II | T-cell Epitope Vaxijen score |
|---|---|---|---|---|---|---|
| 1 | LNEVAKNLNESLIDLQELGK | 1205–1186 | 0.4281 | LNESLIDLQ | 1 + 7 | 1.0001 |
| LIDLQELGK | 8 + 14 | 0.9206 | ||||
| 2 | ITSGWTFGAGAALQIPFAMQ | 882–901 | 0.6031 | FGAGAALQI | 29 + 23 | 0.6377 |
| WTFGAGAAL | 7 + 38 | 0.4918 | ||||
| ITSGWTFGA | 27 + 9 | 0.4577 | ||||
| 3 | QSIIAYTMSLGAENSVAYSN | 690–709 | 0.5222 | YTMSLGAEN | 11 + 6 | 0.9735 |
| LGAENSVAY | 3 + 14 | 0.4173 | ||||
| YTMSLGAEN | 11 + 6 | 0.9735 | ||||
| 4 | GVSVITPGTNTSNQVA | 639–654 | 0.4651 | VSVITPGTN | 18 + 6 | 0.5501 |
| 5 | GWTAGAAAYYVGYLQP | 302–316 | 0.6210 | WTAGAAAYY | 25 + 1 | 0.6306 |
| 6 | HRSYLTPGDSSSGWTA | 290–305 | 0.6017 | LTPGDSSSG | 9 + 4 | 0.7579 |
| YLTPGDSSS | 27 + 1 | 0.5905 | ||||
| 7 | TVEKGIYQTSNFRVQP | 352–367 | 0.6733 | YQTSNFRVQ | 8 + 9 | 0.7821 |
| 8 | ESPIRATRYSYNDRME | 22–37 | 1.0078 | IRATRYSYN | 10 + 8 | 1.5237 |
| 9 | GCLIGAEHVNNSYECD | 693–654 | 0.8480 | IGAEHVNNS | 20 + 29 | 1.2611 |
| LIGAEHVNN | 9 + 6 | 0.9246 | ||||
| 10 | LQSYGFQPTNGVGYQP | 537–552 | 0.5258 | YGFQPTNGV | 39 + 33 | 1.0509 |
| LQSYGFQPT | 37 + 4 | 0.7917 | ||||
| 11 | TRFQTLLALHRSYLTP | 281–296 | 0.5115 | LLALHRSYL | 39 + 33 | 0.5241 |
| 12 | FAMQMAYRFNGIGVTQ | 943–958 | 1.3096 | FAMQMAYRF | 36 + 8 | 1.0278 |
| MQMAYRFNG | 11 + 28 | 0.4868 | ||||
| YRFNGIGVT | 15 + 12 | 1.7692 | ||||
| 13 | EVRQIAPGQTGKIADY | 451–466 | 1.3837 | VRQIAPGQT | 13 + 39 | 0.8675 |
| 14 | QTLLALHRSYLTPGDSSSGWTAGAAAY | 239–265 | 0.4822 | LLALHRSYL | 34 + 40 | 0.5241 |
| LHRSYLTPG | 1 + 10 | 0.7761 | ||||
| YLTPGDSSS | 7 + 2 | 0.5905 | ||||
| 15 | FTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVC | 392–525 | 0.4563 | FELLHAPAT | 5 + 13 | 0.5409 |
| YFPLQSYGF | 2 + 23 | 0.5107 | ||||
| YGFQPTNGV | 8 + 33 | 1.0509 | ||||
| YQPYRVVVL | 8 + 32 | 0.5964 | ||||
| VVVLSFELL | 8 + 15 | 1.0909 | ||||
| VRQIAPGQT | 2 + 26 | 0.8675 | ||||
| 16 | WFHAIHVSGTNGTKRFDNPV | 64–83 | 0.4100 | FHAIHVSGT | 15 + 39 | 0.9305 |
| IHVSGTNGT | 11 + 30 | 0.8621 | ||||
| 17 | ENSVAYSNNSIAIPTNF | 702–718 | 0.4481 | VAYSNNSIA | 27 + 20 | 0.8537 |
| YSNNSIAIP | 4 + 5 | 0.5477 | ||||
| 18 | AGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIAN | 879–925 | 0.5747 | FAMQMAYRF | 8 + 18 | 1.0278 |
| FGAGAALQI | 9 + 7 | 0.6377 | ||||
| WTFGAGAAL | 22 + 1 | 0.4918 | ||||
| MQMAYRFNG | 0 + 40 | 0.4868 |