Table 4:

Summary of Unadjusted Association of Six-Minute Walk Distance (6MWD) with ICU Factors

ICU Factors	No. of distinct studies	Association with (6MWD)	Assessment timepoint
			3-month	6-month	12-month	24-month	36-month	48-month	60-month
Severity of illness (APACHE II score)	5	Negative None	[12, 28] [16]	[12] [28, 29]	[12] [28, 29]	[12]	[12]	[12]	[12] [2]
ICU length of stay (days)	4	Negative None	[28] [16] [12]	[12, 28, 29]	[12, 28, 29]	[12]	[12]	[12]	[12, 2]
Neuromuscular blocker	3	Negative None	[28]	[28] [29]	[28, 29]				[2]
Mechanical ventilation duration (days)	4	Negative None	[12, 28] [16]	[12] [28, 29]	[12] [28, 29]	[12]	[12]	[12]	[12] [2]
Systemic corticosteroid	3	Negative None	[28] [12, 30]	[28, 29] [12, 30]	[29] [12, 30], [28]	[12, 30]	[12]	[12]	[12, 2]

Abbreviations: ICU:intensive care unit; No: number;

^aSymbols used in table across time-points:

Negative association : i.e. worse walk results (statistically significant), numbers in square brackets are citation numbers

No association : no statistically significant association, numbers in square brackets are citation numbers