Table 3.

BKI concentrations in pooled fecal samples by treatment groups. Piglets were infected on SD 3; SD: study days; dpi: days post-infection.

			Group A (20 mg BKI 1369/kg BW; 0 dpi)
			Concentration (μM)
SD		Hours post first-dose	BKI 1369	BKI 1318	BKI 1817
2		−24	0.0	0.0	0.0
3		2	0.8	0.0	0.0
4		24	8.1	0.3	54.0
5		48	5.5	0.4	60.8
29		624	0.0	0.0	0.0
Group B (20 mg BKI 1369/kg BW; 2 dpi)
4	−24		0.0	0.0	0.0
5	2		0.0	0.0	0.0
6	24		0.8	0.0	0.8
7	48		3.0	0.7	53.5
29	576		0.0	0.0	0.0
Group C (20 mg BKI 1369/kg BW; 2 and 4 dpi)
4		−24	0.0	0.0		0.0
5		2	0.0	0.0		0.0
6		24	4.5	0.3		130.0
7		48/2 h post 2nd dose	37.0	1.9		280.8
8		72/24 h post 2nd dose	19.7	3.6		331.6
9		96/48 h post 2nd dose	29.2	7.0		537.0
29		576/528 h post 2nd dose	0.0	0.3		6.6