Table 3. Differences in baseline characteristics according to cirrhosis.
| Feature | Cirrhosis | No cirrhosis | Odds ratio (95% CI) | Unadjusted P-value | Adjusted odds ratio (95% CI) | Adjusted P-value |
|---|---|---|---|---|---|---|
| n = 43 | n = 288 | |||||
| Epidemiological features | ||||||
| Age, mean (SD), years | 50.7 (10.5) | 40.6 (8.9) | 1.1 (1.1–1.1) | <0.0001 | 1.1 (1.1–1.2) | <0.0001 |
| Sex male n(%) | 32 (74) | 168 (58) | 2.1 (1.0–4.3) | 0.05 | 2.2 (0.9–5.6) | 0.09 |
| BMI, mean (SD), kg/m2 | 28.2 (3.9) | 25.5 (4.3) | 1.1 (1.1–1.2) | 0.0002 | 1.1 (1.0–1.3) | 0.004 |
| Characteristics of HCV infection | ||||||
| HCV-RNA at baseline, mean SD, log10 IU/mL | 6.3 (0.7) | 6.0 (0.9) | 1.4 (0.9–2.1) | 0.15 | ||
| HCV genotype n (%), genotype 2/3 | 13/30 (30/70) | 81/206 (28/72) | 1,1 (0.5–2.2) | 0.79 | ||
| APRI-score, mean (SD), score | 2.1 (1.6) | 0.9 (1.0) | 1.8 (1.4–2.2) | <0.0001 | 1.7 (1.3–2.1) | <0.0001 |
| Serum 25 (OH)D levels | ||||||
| Serum 25 (OH)D, mean (SD), nmol/L | 51.7 (17.6) | 60.0 (23.0) | 0.7 (0.5–1.0)* | 0.03 | 0.8 (0.5–1.3)* | 0.35 |
HCV, hepatitis C virus; APRI, ast to platelet ratio; SD, standard deviation. *Odds ratio calculated from standard score of 25 (OH)D.