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. 2020 Aug 21;15(8):e0237983. doi: 10.1371/journal.pone.0237983

Table 4. Unweighted analysis of the association between metabolic syndrome and electronic cigarette exposure.

Never user (n = 13,459) Ever user (n = 954) Current user (n = 325) P trend
  Reference OR (95% CI) OR (95% CI)
Model 1 1 1.47 (1.25–1.73) 1.72 (1.33–2.22) <0.001
Model 2 1 1.22 (1.03–1.44) 1.40 (1.08–1.82) <0.01
Model 3 1 1.20 (1.01–1.42) 1.40 (1.08–1.82) <0.01
Model 4 1 1.20 (1.01–1.42) 1.40 (1.08–1.81) <0.01

a) Model 1 was adjusted for age and sex; Model 2 was additionally adjusted for conventional cigarette exposure; Model 3 was additionally adjusted for alcohol consumption; and Model 4 was additionally adjusted for physical activity, household income, and education level.

b) The P-value for trend was measured using a logistic regression analysis considering electronic cigarette exposure as a continuous variable.

OR: odds ratio, CI: confidence interval.