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. 2020 Aug 21;6(34):eabb7944. doi: 10.1126/sciadv.abb7944

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Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 3 — (A) Schematic illustrating how the presence of ECTR (red) in an ALT positive sample will increase the absolute number of physical copies of telomeres being measured by digital PCR. (B) Line graph showing the number of compartments containing telomere molecules, as measured using the STAR assay, while the bar chart shows the C-circle assay when performed for the same samples. Both assays show similar trends. AU, arbitrary units.