Table 2.
Location of all IMM, stratified by morphology and presence of meningeal contact
| Location | Total (%) | Morphology | Meningeal Contact | |||
|---|---|---|---|---|---|---|
| Nodular | Elongated | Linear | Yes | No | ||
| All IMM | ||||||
| Supratentorial lobar | 151 (78.6) | 119 | 28 | 4 | 145 | 6 |
| Frontal | 61 | 49 | 11 | 1 | 56 | 5 |
| Temporal | 45 | 35 | 7 | 3 | 44 | 1 |
| Parietal | 25 | 20 | 5 | 0 | 25 | 0 |
| Occipital | 16 | 13 | 3 | 0 | 16 | 0 |
| Insula | 4 | 2 | 2 | 0 | 4 | 0 |
| Basal ganglia region | 13 (6.8) | 13 | 0 | 0 | 2 | 11 |
| Thalamus | 5 | 5 | 0 | 0 | 2 | 3 |
| Lentiform nucleus | 6 | 6 | 0 | 0 | 0 | 6* |
| Caudate nucleus | 1 | 1 | 0 | 0 | 0 | 1 |
| External capsule | 1 | 1 | 0 | 0 | 0 | 1* |
| Posterior fossa | 23 (12.0) | 18 | 4 | 1 | 22 | 1 |
| Cerebellum | 20 | 16 | 3 | 1 | 20 | 0 |
| Midbrain | 1 | 1 | 0 | 0 | 0 | 1 |
| Pons | 2 | 1 | 1 | 0 | 2 | 0 |
| Ventricular | 5 (2.6) | 4 | 0 | 1 | 5** | 0 |
| Total (%) | 192 | 154 (80.2%) | 32 (16.7%) | 6 (3.1%) | 174 (90.6%) | 18 (9.4%) |
| BRAF V600 mutation | ||||||
| Supratentorial lobar | 100 (79.3) | 83 | 17 | 1 | 97 | 3 |
| Frontal | 37 | 30 | 7 | 0 | 35 | 2 |
| Temporal | 32 | 28 | 3 | 1 | 31 | 1 |
| Parietal | 19 | 15 | 4 | 0 | 19 | 0 |
| Occipital | 9 | 7 | 2 | 0 | 9 | 0 |
| Insula | 3 | 2 | 1 | 0 | 3 | 0 |
| Basal ganglia region | 8 (6.3) | 8 | 0 | 0 | 0 | 8 |
| Thalamus | 2 | 2 | 0 | 0 | 0 | 2 |
| Lentiform nucleus | 5 | 5 | 0 | 0 | 0 | 5* |
| Caudate nucleus | 0 | 0 | 0 | 0 | 0 | 0 |
| External capsule | 1 | 1 | 0 | 0 | 0 | 1* |
| Posterior fossa | 14 (11.1) | 11 | 2 | 1 | 13 | 1 |
| Cerebellum | 12 | 10 | 1 | 1 | 12 | 0 |
| Midbrain | 1 | 1 | 0 | 0 | 0 | 1 |
| Pons | 1 | 0 | 1 | 0 | 1 | 0 |
| Ventricular | 4 (3.2) | 3 | 0 | 1 | 4** | 0 |
| Total (%) | 126 | 105 (83.3%) | 19 (15.1%) | 3 (2.4%) | 114 (90.5%) | 12 (9.5%) |
| No BRAF V600 mutation | ||||||
| Supratentorial lobar | 51 (77.3) | 37 | 11 | 3 | 48 | 3 |
| Frontal | 24 | 19 | 4 | 1 | 21 | 3 |
| Temporal | 13 | 7 | 4 | 2 | 13 | 0 |
| Parietal | 6 | 5 | 1 | 0 | 6 | 0 |
| Occipital | 7 | 6 | 1 | 0 | 7 | 0 |
| Insula | 1 | 0 | 1 | 0 | 1 | 0 |
| Basal ganglia region | 5 (7.6) | 5 | 0 | 0 | 2 | 3 |
| Thalamus | 3 | 3 | 0 | 0 | 2 | 1 |
| Lentiform nucleus | 1 | 1 | 0 | 0 | 0 | 1* |
| Caudate nucleus | 1 | 1 | 0 | 0 | 0 | 1 |
| External capsule | 0 | 0 | 0 | 0 | 0 | 0 |
| Posterior fossa | 9 (13.6) | 7 | 2 | 0 | 9 | 0 |
| Cerebellum | 8 | 6 | 2 | 0 | 8 | 0 |
| Midbrain | 0 | 0 | 0 | 0 | 0 | 0 |
| Pons | 1 | 1 | 0 | 0 | 1 | 0 |
| Ventricular | 1 (1.5) | 1 | 0 | 0 | 1** | 0 |
| Total (%) | 66 | 50 (75.8%) | 13 (19.7%) | 3 (4.5%) | 60 (90.9%) | 6 (9.1%) |
Data have been provided for all IMM, as well as those in patients with a BRAF V600 mutation and those without.
*Based on the location, none would contact the meninges. **All considered to contact the meninges.