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Antitumorigenic effect of 10580 against GICRs. (A) E6R and E16R tumor volumes in mice treated daily with saline (open circles), 10580 (closed circles), or BRQ (closed triangles) (n = 6). Statistical significance was determined by the t-test. Error bar: ±SEM. (B) Proportion of Sox2+ cells among human mitochondria+ cells in the tumors. Error bar: ±SD. (C) Proportion of CASP3+ cells in the tumors. Error bar: ±SD. *P < 0.05, **P < 0.01, ***P < 0.001.
