TABLE 2.
Food metabolite databases1
| Database | Description | Unique features | Reference |
|---|---|---|---|
| GNPS | Global Natural Products Social Molecular Networking: database of raw, processed, or identified MS/MS data | Food-specific data and includes MS/MS spectra from a large (>3500) number of different foods | (57) |
| HMDB | Human Metabolome Database on small-molecule metabolites found in the human body | A variety of endogenous metabolites with >1000 biotransformation products; data on 3056 metabolites linked to 2192 SNPs with 6777 specific metabolite-SNP interactions; data on 2901 metabolites that vary with physiology and data on 5498 metabolites that vary with pathophysiologic conditions | (58) |
| PhytoHub | Plant-based metabolite database on phytochemicals present in foods commonly ingested with human diets | Plant metabolites with 578 biotransformation products | (69) |
| Exposome-Explorer | Biomarkers of exposure to environmental risk factors for diseases | Data on 145 dietary biomarkers including their concentrations in various populations, type of biospecimens analyzed, the analytical techniques used, their reproducibility over time, and correlations with food intake | (70) |
| Phenol-Explorer | First comprehensive database on polyphenol content in foods | Plant polyphenol metabolites with 375 biotransformation products | (71) |
| FooDB | Database on food constituents, chemistry, and biology | Data and referential MS and NMR spectra on >26,000 food chemicals found in >720 raw or lightly processed foods | (72) |
1
SNP, single-nucleotide polymorphism.