Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 21;6(34):eaba8968. doi: 10.1126/sciadv.aba8968

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license, which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.

PMC Copyright notice

Fig. 8 — (A to D) Representative images of IHC analysis of breast cancer specimens from patients with TNBC and non-TNBC patients immunostained with antibodies against GPX4 (A), GSS (B), Ferroportin (FPN) (C), and TfR (TFRC) (D). Approximately 65 breast cancer tissues were immunostained for each protein, and staining intensity was scored as described in Materials and Methods. The H-score of patients with TNBC relative to non-TNBC patients is shown in the scatter graphs. Percentages of tumors with low- or high-intensity scores are shown in the middle or right graphs along with representative images. Overall view of the entire section is shown as an insert for each image. Scale bars, 50 μm. Unpaired two-tailed t test was used to compare differences between H-scores of patients with TNBC and non-TNBC patients. Fisher’s exact test was applied to compare percentage of tumor sections with high or low protein expression between TNBC and non-TNBC groups.