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. Author manuscript; available in PMC: 2021 Feb 15.
Published in final edited form as: Clin Cancer Res. 2020 May 21;26(16):4369–4380. doi: 10.1158/1078-0432.CCR-20-0341

Figure 5. Tumor microenvironment analysis of GL261 tumors in CNS.

Figure 5.

A-I) C57BL/6 mice were inoculated with GL261 cells and treated as in Figure 5, and tumors were isolated on day 23 and analyzed by flow cytometry (n = 5 per group). Shown are A) CD8α+ T cells among all T cells, B) PD-1 receptor expression on CD8α+ T cells, C) CD25+Foxp3+ regulatory T cells among CD4+ T cells, D) ratio of CD8α+ T cells to regulatory T cells, and E) the ratio of M1 (CD206- F4/80+) to M2 (CD206+ F4/80+) macrophages.