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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Transl Res. 2020 May 17;224:55–70. doi: 10.1016/j.trsl.2020.05.001

Figure 2. Location and function of NIBP/TRAPPC9 during protein trafficking.

Figure 2.

A. Schematic of mammalian TRAPPII complex. TRAPPC9 subunit interacts directly with TRAPPC10, TRAPPC2, and TRAPPC6. B. Function of TRAPP complexes. TRAPPI is involved in vesicular transport from ER to Golgi, TRAPPII is involved in trans-Golgi, Golgi-to-plasma membrane, and endosome-to-Golgi transport, and TRAPPIII is involved in formation of autolysosome for autophagy.

Notes. ER, endoplasmic reticulum; AL, autolysosome; TRAPP, trafficking protein particle.