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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Circ Genom Precis Med. 2020 Jun 9;13(4):e002817. doi: 10.1161/CIRCGEN.119.002817

Figure.

Figure.

Density Distributions and Risk for Developing MINS as a Function of Genome-wide polygenic risk scores for coronary artery disease (PRSCAD) A. Distribution of PRSCAD in patients developing MINS compared to those without MINS. For MINS group, mean was 0.14 (SD=1.03) and median was 0.18 [95% CI: −0.54 to 0.81]. For non-MINS group mean was −0.01 (SD=0.99) and median was −0.03 [95% CI: −0.64 to 0.65], p=0.004. B. Risk for MINS according to PRSCAD in MGI population. Patients with PRSCAD > 1 standard deviation above the mean have a 1.36 fold greater risk of developing MINS [95% CI=1.06–2.40, p=0.016]. Patients with PRSCAD > 2 standard deviations above the mean have a 2.11 fold greater risk of developing MINS [95% CI=1.26–3.55, p=0.005].

MINS, Myocardial Injury after Noncardiac Surgery; PRSCAD, Polygenic Risk Score for Coronary Artery Disease; SD, Standard Deviation, CI, Confidence Interval; MGI, Michigan Genomics Initiative.