Table 3.
Predicted binding ebergies from Glidescore for ligands SKF 38393 and 10 - 13 at the D1 and 5-HT6 receptors
| Binding energies (kcal/mol) | ||
|---|---|---|
| Cmpd # | D1 | 5-HT6 |
| SKF 38393 | −9.6 | −8.5 |
| 10 | −8.2 | −9.3 |
| 11 | −8.7 | −9.4 |
| 12 | −8.0 | −9.1 |
| 13 | −8.4 | −9.0 |
Predicted binding ebergies from Glidescore for ligands SKF 38393 and 10 - 13 at the D1 and 5-HT6 receptors
| Binding energies (kcal/mol) | ||
|---|---|---|
| Cmpd # | D1 | 5-HT6 |
| SKF 38393 | −9.6 | −8.5 |
| 10 | −8.2 | −9.3 |
| 11 | −8.7 | −9.4 |
| 12 | −8.0 | −9.1 |
| 13 | −8.4 | −9.0 |