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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Hepatology. 2020 Oct 1;72(5):1682–1700. doi: 10.1002/hep.31196

Figure 6. Effects of MAT1A and p65 on the FOXM1 promoter.

Figure 6.

A) HepG2 cells were treated with MAT1A OV or si, or FOXM1 OV or si, and respective controls for 24 hours. ChIP analysis with anti-FOXM1 or MATα1 antibody, and then re-ChIP with anti-MATα1, p65, p50 antibodies after FOXM1 ChIP were performed as described in Materials and Methods. Representative results from three experiments are shown. B) Activities of the wild-type (WT) and FOX binding site mutants (MU) of the FOXM1 promoter after MAT1A OV and si treatment for 24 hours in HepG2 cell. Results are expressed as mean % of EV or SC ± SEM from three experiments done in duplicates *p < 0.05 vs. EV or. SC. C) Promoter activities of the WT and FOX binding site MU of the FOXM1 promoter after p65 OV for 24 hours in the HepG2 cell. Results are expressed as mean % of EV ± SEM from three experiments done in duplicates. *p < 0.05 vs. EV. Results represent at least three independent experiments done in duplicate.